Michele Kelemen

As Syrian fighting intensifies in Syria, diplomatic efforts are also heating up.

U.S. Secretary of State Hillary Clinton, Russian Foreign Minister Sergei Lavrov and the main international envoy to Syria were all in Dublin for an international gathering Thursday. The meeting came as Syria's opposition tries to get better organized to offer a real alternative to President Bashar Assad's regime.

When President Obama sets off to Asia this weekend to highlight his so-called pivot to the region, he will make a bit of history: Obama will become the first sitting U.S. president to visit Myanmar.

The country, also known as Burma, was a pariah state for decades, ruled by a ruthless military dictatorship. That is changing, and the Obama administration has encouraged a dramatic reform process in the country. But it may be too early for a victory lap.

President Obama sounds like he's in for a fight over the woman who could be the next secretary of state. Republicans have been blasting U.N. Ambassador Susan Rice for the way she characterized the attack on the U.S. Consulate in Benghazi, Libya, on Sept. 11.

But the president came to her defense in his news conference Wednesday afternoon.

"When they go after the U.N. ambassador, apparently because they think she's an easy target, then they've got a problem with me," he told reporters.

The protests and violence aimed at U.S. interests in the Middle East have set off a domestic debate about what the U.S. could or should do to relate to new political movements in the region. The Obama administration says it will continue to engage the region. The campaign of Mitt Romney, the Republican presidential candidate, says the U.S. needs to do more to lead.

But there are others who say that both parties have it wrong, and that U.S. policies from both Republican and Democratic administrations have failed.

The Obama administration often talks about its strong bonds with Israel, but relations between the two leaders don't look that way at all.

Israeli Prime Minister Benjamin Netanyahu and the Obama administration openly clashed over Iran this week. The White House also announced that President Obama would not have time to meet Netanyahu when the Israeli prime minister is in the U.S. later this month.

The two men did have a lengthy phone conversation, but some say what they really need is a marriage counselor.

As U.S. embassies and consulates face protests in the Muslim world over an anti-Islamic film, Secretary of State Hillary Clinton is walking a fine line. She is distancing herself and the State Department from the video that has sparked anger among Muslims, but stressed the US commitment to free speech.

"To us, to me personally, this video is disgusting and reprehensible," she said Thursday in Washington, D.C. "It appears to have a deeply cynical purpose: to denigrate a great religion and to provoke rage."

Foreign policy has not been a major focus of this election campaign, but whoever wins in November will have a messy inbox when it comes to the delicate tangle of issues in the Middle East.

For decades, the U.S. relied on authoritarian regimes to provide stability in the region. Now, it must deal with a new government in Egypt, an intensifying conflict in Syria, nervous allies in the Persian Gulf — and a major decision about Iran.